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Posted: Mon May 21, 2007 12:29 pm
by Chelseyrl
voyboy wrote:why are you sneaking into hotels for free continental breakfasts and free Internet service? is Jonas out of money?
:shock:
Why pay when Daniel could use his criminal skills? :lol:

jonas is evil

Posted: Mon May 21, 2007 10:32 pm
by modelmotion
so u r in N. Cal, right?

Posted: Mon May 21, 2007 10:53 pm
by JustAnotherLonelyGirl.
I assumed the number was Julia's social security number.

Posted: Mon May 21, 2007 11:04 pm
by TOSG
danielbeast wrote:I snuck into this hotel and pretended to be a guest lol. I'm in the business center... love the free coffee and donuts!
Hahaha, I just did that this morning!

Mmmmm, free (truly!) continental breakfast...

Posted: Tue May 22, 2007 2:27 pm
by Chelseyrl
JustAnotherLonelyGirl. wrote:I assumed the number was Julia's social security number.
It couldn't be her social security number because ss#'s are 10 numbers and the numbers (8[or is that a B?]1606324684) consist of 11 numbers.

Posted: Tue May 22, 2007 3:17 pm
by impulse
Chelseyrl wrote:
JustAnotherLonelyGirl. wrote:I assumed the number was Julia's social security number.
It couldn't be her social security number because ss#'s are 10 numbers and the numbers (8[or is that a B?]1606324684) consist of 11 numbers.
SSN are 9-digit numbers in the US.

Posted: Tue May 22, 2007 9:17 pm
by JustAnotherLonelyGirl.
maybe a credit card number?

Posted: Tue May 22, 2007 10:55 pm
by Chelseyrl
impulse wrote:
Chelseyrl wrote:
JustAnotherLonelyGirl. wrote:I assumed the number was Julia's social security number.
It couldn't be her social security number because ss#'s are 10 numbers and the numbers (8[or is that a B?]1606324684) consist of 11 numbers.
SSN are 9-digit numbers in the US.
Ah, yeah you're right. I dunno what I was thinking.

Posted: Tue May 22, 2007 11:36 pm
by QtheC
Okay, I did a little research on what the 15.2 pg/mL might mean, but it got tedious and I didn't finish it, if anyone wants to pick up the ball and run with it a little further, feel free. Here are my notes:

Code: Select all

Julia Anderson 
81630324684 
06/07/92 


TRAIT: NEGATIVE (15.2pg/mL) 

===========================================================================
Clinical Data Unit Conversion
===========================================================================

http://www.unc.edu/~rowlett/units/scales/clinical_data.html

                                Conventional    Conversion      Metric          Trait
                                Unit            Factor          Unit            15.2 pg/mL

Angiotensin I                   pg/mL           0.772           pmol/L          11.7 pmol/L
Angiotensin II                  pg/mL           0.957           pmol/L          14.6 pmol/L
Antidiuretic hormone            pg/mL           0.923           pmol/L          14.0 pmol/L
Calcitonin                      pg/mL           1.0             ng/L            15.2 ng/L
Corticotropin (ACTH)            pg/mL           0.22            pmol/L          3.34 pmol/L
Epinephrine                     pg/mL           5.46            pmol/L          83.0 pmol/L
Estradiol                       pg/mL           3.671           pmol/L          55.8 pmol/L
Glucagon                        pg/mL           1.0             ng/L            15.2 ng/L
Norepinephrine                  pg/mL           0.00591         nmol/L          0.090 nmol/L
Parathyroid hormone             pg/mL           1.0             ng/L            15.2 ng/L
Renin                           pg/mL           0.0237          pmol/L          0.36 pmol/L
Somatostatin                    pg/mL           0.611           pmol/L          9.29 pmol/L
polypeptide                     pg/mL           1.0             ng/L            15.2 ng/L
Vitamin B12 (cyanocobalamin)    pg/mL           0.738           pmol/L          11.2 pmol/L
Vitamin D       
    1,25-Dihydroxyvitamin D     pg/mL           2.6             pmol/L          39.52 pmol/L
    25-Hydroxyvitamin D         ng/mL           2.496           nmol/L 

(conventional units x conversion factor = metric units)


===========================================================================

Expected/Normal Values:

http://eurheartj.oxfordjournals.org/cgi/reprint/21/17/1484-a.pdf
Angiotensin II                  
        normal range 5-15 pg/mL
        elevated levels (median 33 pg/mL) correlate to congestive heart disease


============================================================================
google search: clinical data reference ranges
============================================================================

Reference Ranges:

http://www.cdha.nshealth.ca/programsandservices/clinicalchemistry/referenceRanges.html

Endicrinology
-------------
http://www.cdha.nshealth.ca/programsandservices/clinicalchemistry/endoInterpretiveDataRefRanges.pdf

Calcitonin (CAL)                pg/mL           1.0             ng/L 
 reference range male: < 11 pg/mL
 refernece range female: < 7 pg/mL

Estradiol (E2)                  pg/mL           3.671           pmol/L 
 reference range adult female: 
  postmenopausal untreated <110 pmol/L
  postmenopausal treated <341 pmol/L
  ovulating follicular phase: <976 pmol/L
  ovulating midcycle: 433-1303 pmol/L
  ovulating luteal: 95-606 pmol/L
  oral contraceptives: <374 pmol/L
 reference range adult male: <205 pmol/L

Parathyroid hormone (PTH)       pg/mL           1.0             ng/L 
 reference range adult: 1.1-7.5 pmol/L

Vitamin B12 (cyanocobalamin)    pg/mL           0.738           pmol/L 
 reference range: 156-672 pmol/L



about Antidiuretic hormone (ADH):
http://pediatrics.aappublications.org/cgi/content/full/116/6/1401



more on Estradiol:
http://www.lef.org/magazine/mag2006/may2006_report_blood_04.htm
The top section just shows conversion of the given value 15.2 pg/mL into various possible clinical data items that use that unit for measurement.

Angiotensin II appears to be a possibility since the value is close to the normal range.

It does not appear likely to be Calcitonin, Estradiol, or Vitamin B12 since the values are not in the expected ranges, from the reference I found for expected adult values. I'm not sure about the PTH value because I don't have the conversion factor to match up the units.

But take all this with a grain of salt, because I think you need quite a lot of medical training to make any reasonable statements about clinical data. Things interact and age, weight, sex, health, etc. are all factors.

Anyone want to search for expected clinical ranges for some of the other items?

Also, in thinking about this, I wonder if whatever the factor of interest turns out to be is tied to maturation... it seems the Order is keeping young females waiting for them to mature, and then checking for some "trait."

My guess is that we are looking for something that is rare/unusual (to get a "Trait Positive" result), so it would make sense then that Julia's "Trait Negative" result would be a more common result, and would fall in an expected range.

Posted: Tue May 22, 2007 11:45 pm
by JustAnotherLonelyGirl.
OMG I just had a burst of insight.
They label certain genes with numbers.
Maybe that is the number of the trait for which Julia is negative.
-prepares for a late night of LG15 research-

Posted: Wed May 23, 2007 12:28 am
by shadowofjustice
JustAnotherLonelyGirl. wrote:OMG I just had a burst of insight.
They label certain genes with numbers.
Maybe that is the number of the trait for which Julia is negative.
-prepares for a late night of LG15 research-
One of the people on the comment board already checked, it's not a gene number.

Posted: Wed May 23, 2007 5:03 am
by Gidget
Good job QtheC! that is defiantly some good information.

That was a lot of info, I've done a lot of research too, but I just can't get anything to connect.

Posted: Wed May 23, 2007 10:11 am
by kellylen
i was JUST on that website Q

Posted: Wed May 23, 2007 10:31 am
by kellylen
a picogram per mL is very very little

ok we had a med student and a pharmacy student here... we can do this

Posted: Wed May 23, 2007 7:26 pm
by Ruberic
Several other factors other than hormones are measured in picograms/L. Specifically Interleukins.

Interleukins are typcially associated with inflammation processes, however genetic studies have shown some interesting things about several of the interleukins.

IL-8: f a pregnant mother has high levels of interleukin-8, she has a higher risk of inducing schizophrenia in her offspring.[1] High levels of Interleukin 8 have been shown to reduce the chance of good treatment responses to antipsychotic medication in schizophrenia.[2] Interleukin-8 is often associated with inflammation.

Also:

The role of interleukins, such as IL-8, and chemokine receptors (CXCR1 and 2) has been postulated in cancer growth, but no clear connection has been established. Our results will open the possibility of a novel approach for combating metastatic breast cancer.

IL-6: IL-6 is one of the most important mediators of fever and of the acute phase response. In the muscle and fatty tissue IL-6 stimulates energy mobilization which leads to increased body temperature. IL-6 can be secreted by macrophages in response to specific microbial molecules, referred to as pathogen associated molecular patterns (PAMPs). These PAMPs bind to highly important detection molecules of the innate immune system, called Toll-like receptors (TLRs), that are present on the cell surface (or in intracellular compartments) which induce intracellular signaling cascades that give rise to inflammatory cytokine production. IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Inhibitors of IL-6 (including estrogen) are used to treat postmenopausal osteoporosis.

TNF-alpha: tissue necrosis factor. Has several different functions depending on organ being stimulated. Usually works in unison with IL-1 and IL-6.

Bad news...I cannot recall the normal levels of any of these genomes. If anyone wants to do the research there...go for it.

EDIT: To be clear: The above data comes directly from Wikipedia, but were written (partially) by a colleague of mine